ESR

About this test

Erythrocyte sedimentation rate (ESR) measures inflammation present in the body.

Red blood cells settle out slowly over time to leave behind clear plasma, however, in the presence of acute phase reactants (proteins) the cells tend to settle faster (at a higher rate). This occurs during infection, and is measured by this specific test.

The test is usually requested in the presence of symptoms such as headaches, neck pain, pelvic pain, low heamoglobin, decreased appetite, weight loss and joint stiffness to confirm a diagnosis related to inflammation. Inflammation is part of the immune system's response to injury (trauma), infection or chronic disease states such as rheumatoid arthritis or cancer.

The test is not diagnostic alone and must be interpreted and used in combination with clinical symptoms, signs and other specific investigations e.g. CRP. This test may be used to monitor the response to treatment for both acute and chronic conditions.

Who is this test for?

The ESR test is usually performed when underlying inflammation related to a disease process is suspected.

It is typically suitable for people suffering symptoms of headaches, neck pain, pelvic pain, low heamoglobin, decreased appetite, weight loss and joint stiffness.